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Cardarine (GW-501516)
PPAR Delta Agonist
£50.00
What’s Included
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60 capsules per bottle -
10mg pure GW501516 per capsule
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2-month supply (1 cap daily)
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Third-party lab certificate included
Lab Tested
Third-party verified
Fast Shipping
3-5 business days
24/7 Support
Expert guidance
Product Description
Cardarine GW501516 is a powerful PPAR delta agonist that dramatically enhances endurance and accelerates fat burning. Originally developed for treating metabolic disorders, it has become the ultimate supplement for athletes seeking enhanced performance and body composition.
Our pharmaceutical-grade Cardarine is produced under strict quality controls and third-party tested for purity. Each capsule contains 10mg of pure GW501516, providing consistent energy and fat-burning benefits.
A Different Class of Compound
Cardarine GW-501516 occupies a unique position in the research chemicals market. Unlike SARMs, which target androgen receptors, Cardarine activates PPARdelta, a nuclear receptor that regulates genes involved in fat metabolism, mitochondrial development, and oxidative muscle fibre expression.
The result is a compound with a completely different performance profile: less about muscle building, more about conditioning, endurance, and metabolic efficiency.
23 reviews for Cardarine (GW-501516)
Key Benefits
Enhanced endurance
Accelerated fat loss
Improved recovery
Increased energy
Better cardiovascular health
Metabolic enhancement
Ingredients & Dosage
Active Ingredients
Cardarine (GW501516)
10mgPPAR delta agonist
Black Pepper Fruit Extract (Piper nigrum)
5mgEnhances absorption and bioavailability
Purity & Quality
Third-party lab tested 
99.5%+ purity guaranteed 
24-month shelf life Metabolic Enhancement
Cardarine (GW501516) works by activating PPAR delta receptors, which regulate genes involved in fat oxidation and energy metabolism. This activation increases the body’s ability to burn fat for fuel while preserving muscle tissue.
The compound enhances mitochondrial function and promotes the development of slow-twitch muscle fibers, leading to dramatically improved endurance capacity. Users often report being able to perform longer, more intense workouts without fatigue.
With a half-life of 16-24 hours, Cardarine provides sustained metabolic enhancement throughout the day, making it ideal for both training and recovery periods.
Key Actions
How to Use
Dosage
10mg once daily
Timing
Take 30-45 minutes before workout
Cycle Length
8-12 weeks followed by a 4-week break
Important
Dietary supplement use only
Can be taken on empty stomach. Split dose if taking 20mg daily.
Endurance and Fat Oxidation
For researchers and athletes focused on fat loss and cardiovascular performance, Cardarine’s mechanism is well-documented.
A mouse study published in Scientific Reports found that GW501516 increased running endurance and promoted a shift toward oxidative muscle fibre expression, both with and without concurrent exercise training. [1]
By shifting the body’s primary fuel source toward fatty acids, it supports:
- Sustained high-intensity output.
- Reduced reliance on glycogen during training.
- Preservation of lean tissue through a caloric deficit.
- Improved recovery between sessions.
The endurance benefits are typically felt quickly, with peak performance effects becoming consistent by weeks two to three.
Cardiovascular and Metabolic Research
Cardarine has also been studied for its effects on lipid metabolism. The original characterisation of the compound, published in PNAS, examined its role in reverse cholesterol transport and HDL regulation, the mechanism that first drew clinical interest in metabolic disease research. [2]
This makes it a compound of continued relevance beyond performance contexts.
At 10mg daily, Cardarine delivers consistent results. Cycle lengths should not exceed 8-10 weeks. It does not interact with androgen receptors and does not require PCT. Cardarine is classified by WADA as an S4 metabolic modulator and is prohibited in competitive sport. Sold strictly for research purposes, with batch-specific certificates of analysis available for all stock.
Frequently Asked Questions
Cardarine is a PPAR delta agonist that enhances endurance, promotes fat loss, and improves overall metabolic function.
Most users experience enhanced endurance within 1-3 days of starting Cardarine supplementation.
Yes, Cardarine is excellent for cutting phases as it promotes fat loss while preserving muscle mass and maintaining energy levels.
Cardarine is generally well-tolerated at recommended doses. Mild effects may include headaches, nausea, or changes in liver enzyme levels. High or prolonged doses have shown potential risks in animal studies, so adherence to dosing guidelines is important.
Follow recommended cycle lengths and take breaks between cycles. Consult healthcare providers for long-term supplementation plans.
Yes, Cardarine stacks well with SARMs and other supplements. It’s particularly effective when combined with muscle-building compounds.
GW501516, commonly known as Cardarine, is a PPAR receptor agonist that enhances the body’s ability to burn fat and improve endurance. It supports better energy metabolism, stamina, and cardiovascular performance, making it ideal for athletes focused on fat loss, endurance, and conditioning.
Most users experience increased endurance and energy within 1-2 weeks of consistent use. Noticeable fat-loss and performance improvements are typically seen after 3-4 weeks, depending on training intensity and diet.
Cardarine does not directly build muscle like SARMs, but it helps preserve lean muscle mass during calorie deficits. Its ability to improve recovery and stamina supports longer, more effective training sessions, which can indirectly promote lean muscle development.
For best results, Cardarine is often taken 30-45 minutes before a workout to maximize endurance and performance. On non-training days, it can be taken at any consistent time to maintain steady levels in the system.
Sources:
[1] Chen, W., Gao, R., Xie, X., et al. (2015). A metabolomic study of the PPARdelta agonist GW501516 for enhancing running endurance in Kunming mice. Scientific Reports, 5, 9884. https://doi.org/10.1038/srep09884
[2] Oliver, W. R., Shenk, J. L., Snaith, M. R., et al. (2001). A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. PNAS, 98(9), 5306-5311. https://doi.org/10.1073/pnas.091021198
Customer Reviews
veryy good
All of those stories about crazy endurance were true after all... I was sceptical at first but now I am speechless.
Took one 10mg capsule per day, usually before gym. Of course the endurance is the big thing from this compound and it really worked. For my cardio warmups I felt that I could go forever without any stopping. Also took my diet a bit more seriously than usual and the results let themself show almost instantly. All of the excess weight disappeared into thin air.
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Cardarine (GW-501516)
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John T. –
Meine Ausdauer bei Cardio-Einheiten mit Cardarine hat sich deutlich verbessert. Ich kann längere Trainingseinheiten durchziehen, ohne mich völlig ausgelaugt zu fühlen. Die Qualität ist erstklassig und der Versand war schnell!
Tomasz Lewandowski –
Love it, thanks:)
Lucas Fontaine –
good
Diego Navarro –
Do you also feel a lot more hungry while on it?
Marko Petrovic –
Thoroughly recommended.
Luis Romero –
MK+CARDARINE = dream combo
Daniel Kowalski –
Loved every second on it, felt natural and a gentle kick in ass
Andre Silva –
For the longest time, I was always super unenergized, but after one cycle I feel like a totally new person.
Viktor Horvat –
fast delivery
Alex Romero –
As a runner, this is just a cheat code; I can run faster/farther and look fuller. YEs please:D
Kevin O’Brien –
Lost 30 pounds in 5 weeks!
Matteo DeLuca –
Great cardio boost
Chris Morgan –
Took one 10mg capsule per day, usually before gym. Of course the endurance is the big thing from this compound and it really worked. For my cardio warmups I felt that I could go forever without any stopping. Also took my diet a bit more seriously than usual and the results let themself show almost instantly. All of the excess weight disappeared into thin air.
Gene Nanuk –
Cardio skyrocketed
Duane Gregory –
This ended up being a really good call
Ethelred Colin –
I will keep using it
Gareth Gael –
Pretty solid
Cherokee Lemuel –
Happy I gave this a chance
Skyler Oscar –
It feels like I have 3 lungs
Monroe Conner –
10/10 recommend!!!
Irwin Arlen –
Took one 10mg capsule per day, usually before gym. Of course the endurance is the big thing from this compound and it really worked. For my cardio warmups I felt that I could go forever without any stopping. Also took my diet a bit more seriously than usual and the results let themself show almost instantly. All of the excess weight disappeared into thin air.
Crue Tucker –
All of those stories about crazy endurance were true after all… I was sceptical at first but now I am speechless.
Eliot Bradley –
veryy good